Insecticide Fosthiazate Cas 98886-44-3 Details

Fosthiazate is an organophosphorus nematicide. The pure product is a light yellow liquid. The main mode of action is to inhibit the synthesis of acetylcholinesterase of root-knot nematodes. It has strong contact activity and has developed resistance to some traditional insecticides. Pests are also highly active. Fosthiazate is mainly used to control nematodes, aphids, etc. It is one of the few nematicide products and is suitable for the production of pollution-free vegetables.

Applications of Fosthiazate

Fosthiazate is an insecticide and nematicide, and its main mode of action is to inhibit the acetylcholinesterase of the target pests, affecting the ecology of the second larval stage. It is used to control many pests of Thysanoptera, Lepidoptera, Coleoptera and Diptera on the ground. It is also very effective for underground root pests; it is also effective for many mites. It has good chemical activity against various nematodes. Insecticides produce resistant pests (such as aphids) with good systemic killing activity. It is most effective to mix Fosthiazate into the soil immediately after application, and it can be applied directly to the soil surface before planting or it can be used when crops are sown. The recommended dosage is 1-4kg active ingredient/hm2.

Fosthiazate has a good control effect on various nematodes such as root-knot nematodes, root rot nematodes, stem nematodes, cyst nematodes, etc. Effect. The duration of annual crops is 2-3 months, and the duration of perennial crops is 4-6 months. The dosage is 1.5-2 kg/mu. In the vegetable area, it is generally used twice a season, 4-6 kg each time. The use cost is about 200 yuan. In China, it has been registered in cucumber, tomato and watermelon, and can be widely used in vegetables, bananas, fruit trees, medicinal materials and other crops. Applicable crops: carrots, eggplants, radishes, yams, potatoes, garlic, sweet potatoes, watermelons, bananas and tobacco.

Fosthiazate is derived from thiadiazole; pharmaceutical intermediate.

Synthesis of Fosthiazate

n-Butyllithium method Dissolve 1.5g of 2-oxothiazolidine in 30mL of tetrahydrofuran, cool, then add n-butyllithium in n-hexane solution (1.65mol) dropwise, stir the mixture for 15min, then add dropwise to it containing 5gS- 10 mL of sec-butyl-O-ethylphosphorylthiochloride solution in tetrahydrofuran, the mixture was stirred for another 30 minutes, and reacted at room temperature for 3 days. After the reaction was completed, it was poured into water, extracted with ethyl acetate, washed with water, dried, and desolvated to obtain 2-3 g The required product yield is 70% to 90%. Metal sodium method Add toluene and metal sodium to the reactor, and raise the temperature to reflux temperature under nitrogen. After the metal sodium melts, stir to disperse, add dropwise the tetraphenyl solution of 2-oxothiazolidine, and continue the reaction for 2 hours after dropping. Cool to 15°C, add S-sec-butyl-O-ethylphosphorylthiochloride dropwise, and react for another 1h. After post-treatment, thiazolphos was obtained with a purity of 96.4% and a yield of 91.2% based on phosphorus oxychloride.

Package of Fosthiazate

We also supply some accessories to add more functions for end-users' convenience, which also help our distributors and business partners sell our products in their area. Any special package requirements, please don't be hesitate to tell us.

Large Package:

Solid: 25Kg UN approved fiber drums with LDPE liner;

Liquid: 200L UN approved HDPE or iron drums.

Retail Package:

Solid: 10g;50g;100g;500g;1kg;5kg;25kg

Supplier of Fosthiazate

Agripestcide is a professional pesticide chemical manufacturer provides high quality and effective Fosthiazate with high quality and good service. If you are looking for    Fosthiazate in bulk, feel free to contact us to get the latest price.